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Clomiphene Citrate

Clomiphene Citrate

What is Clomiphene Citrate

Clomiphene citrate is a drug used in the post cycle therapy by the athletes in order to increase total testosterone levels. Clomiphene is one of the drugs indicated in males who may suffer of low testosterone levels after anabolic steroid’ cycle. It has the ability to bind to the estrogen receptors in males who run estrogenic compounds such as nandrolone decanoate, testosterone, methandrostenolone and others. Overall, it is a great drug that increases testosterone levels and helps preventing side effects related to suppression of natural levels of testosterone. As it is a specific drug, each user has to exercise caution to doses, indications of use, precautions and possible side effects. In order to make sure that this drug is right for you, it is recommended to test the testosterone levels after anabolic steroid cycle. Assess the normal levels of hormone in the body, and if it is lower than indicated, start using clomiphene citrate.

Brand names

Clomiphene citrate is traded under the following names: Clomid, Clomed, Clofert and others. The mentioned ones are the most popular brand names, this is why it is most probable to find clomiphene under those mentioned above.


Like in case of many other medicines, avoid clomiphene citrate if you have a known hypersensitivity to it. The symptoms of increased sensitivity to the drug are the following: swelling of the face, lips and tongue, rash, acne and others. Discontinue right away with the drug if some of the enumerated adverse reactions occur.

Particularities of clomiphene citrate

As already mentioned, clomiphene citrate is a drug indicated in the post cycle therapy in order to increase the testosterone levels. It is considered an efficient drug for such purposes as after a strong anabolic steroid’ cycle body stops producing testosterone. Respectively, it is important to run a post cycle therapy to help recover from suppression of naturally produced hormone.

Clomiphene citrate also blocks and minimizes the effects of estrogen. This is the reason it may be used during the steroid cycles in order to reduce the incidence of developing estrogen-related side effects.

Another particularity of clomiphene citrate is that it prevents muscle protein synthesis that is likely to occur without testosterone. Clomiphene Citrate in this sense prevents from losing the newly acquired muscles and helps the athlete recover when endogenous testosterone levels are depressed.

The mechanism of action of clomiphene citrate

Clomiphene takes part from the selective estrogen receptor modulators’ class of drugs; therefore it acts by binding to the estrogen receptor and blocking estrogen. This is one of the reasons it may be used as an anti-gynecomastia agent, even if it is more popular for its efficiency in increasing testosterone levels. So, to this regard, clomiphene citrate stimulates leutenizing hormone and follicle stimulating hormone that contribute to natural testosterone production increase.

Indications of use and dosage

It should be noted that clomiphene citrate comes in form of tablets and it is intended for oral administration. Generally, it is considered that even a dose of 150mg per day of clomiphene citrate increases testosterone levels to approximately 150% of baseline value. However, depending on existing endogenous testosterone levels, one may use a dose lower than 150mg. Therefore, a dose of 100mg per day for a week will provide good elevations in testosterone levels. Tablets may be taken with or without food. For a better absorption of the tablets, it is recommended to take them with a glass of water or juice.

The increase in testosterone should occur slowly but evenly throughout the whole period of therapy. In order to obtain an immediate boost in testosterone, clomiphene citrate may be used in combination with Human Chorionic Gonadotropin, better in the first two weeks after discontinuation with steroids.

Speaking about length of therapy with clomiphene citrate, we should mention that it is very safe for long-term administration for males with low testosterone levels. Some studies show that clomiphene citrate is mostly efficient in males with low endogenous testosterone levels and it acts at it best in this case. However, a period of three weeks is just enough to get back to normal and recover from anabolic steroid cycle.

What to do if you missed a dose?

If you forgot to take a dose of clomiphene citrate, take it as soon as you remember. As this drug is indicated once a day, there is not a big deal if you take it at a different hour. However, if you missed a one-day dose, leave it and continue your normal schedule. Do not take a double dose to make up for the missed one. Try to not miss doses and take it as indicated in order to benefit most from the therapy with it.

Possible side effects with clomiphene citrate

Like in case of other selective estrogen receptor modulators, clomiphene citrate may cause side effects. Generally, severe side effects with clomiphene citrate may occur when taking it in high doses for an extended period of time. One of the most common side effects in such cases is the optic neuropathy, which can be described more easily as vision difficulties. Other side effects associated with high doses and long lasting therapy are the following: changes in mood, depression, unusual tiredness and others. Therefore, users who are prone to such adverse reactions are recommended to take clomiphene citrate in lower doses and for a pre-determined period of time.

Other side effects one may experience with clomiphene citrate are the following:

Hot flashes;




As for toxicity, clomiphene citrate is a very safe drug and even males with pre-existent renal or liver diseases may find it tolerant and efficient.


It is recommended to store clomiphene citrate at the room temperature below 25 degrees Celsius. Do not leave the drug at the reach of children. Keep the tablets away from the direct sunlight exposure. Do not store the tablets in the bathroom in order to avoid moisture. Safely discard the drug. If you have any other questions, ask a pharmacist or a physician.

Clomiphene Citrate (Clomixyl,Clomidex,Clomed,Clomid)